Attempts to overcome drug resistance are central to both clinical and basic molecular research in cancer chemotherapy. Temple's focus is on ovarian cancer with its TTX335o (novel target specific drug) and TTX335oDX (early detection for ovarian cancer). After winning an Eurostars Grant in 2019, Temple has been able to validate the target, elucidate its mechanism and show early promising in-vivo results in ovarian cancer, with the possibilty of expanding it to other solid tumors, such as pancreatic. Ovarian cancer is currently regarded as one of the most common cancer types among women. This type of cancer is rarely diagnosed at its early stages, making the treatment of this
Learn MorePossible Solution to Endometriosis? Oxidative Stress – Molecular hydrogen – Antioxidants – Endometriosis This article is not like my previous blogs. This one is more research orientated and somehow I believe in this one strongly. First, I am not a medical doctor and I am not providing any medical advice. This is simply my views as a sufferer of endometriosis and my quest to bring information to people. This also is a request to the medical authorities and healthcare department to look into it more thoroughly and find a systematic, regular basis (monthly/ weekly) treatment for endometriosis patients – Antioxidants based or molecular hydrogen based therapy
Learn MoreVulva vestibulitis or localized provoked vulvodynia (LPV) is when there is pain in your vestibule, the portion of the vulva surrounding the opening of the vagina. Characterized by a stinging or burning-like pain at the vaginal opening, it’s typically provoked by sexual intercourse and the insertion of objects such as a tampon or speculum into the vagina. Sometimes it can be present during daily activities. Vulva vestibulitis can cause redness and irritation of the skin as well as pain in the glands inside the skin. Classified as a “neuro-inflammatory” condition, vulva vestibulitis involves inflammation which causes pain as the nerves that are
Learn MoreGut microbiome is essentially our digestive system’s ecosystem of bacteria, viruses, and fungi. Located in a pocket of the large intestine called the cecum, gut microbiomes are needed to fight off bad bacteria, viruses, and fungi. Gut microbiomes are crucial for our overall health, but digging deeper, how do they affect your menstrual cycle? When our ovaries are producing estrogen, it will circulate through the bloodstream before it arrives at the liver. It is here that the estrogen is inactivated and travels to the digestive tract for elimination. The gut microbiomes will produce B-glucuronidase, an enzyme that will break down estrogen into its active form so that it can exit
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When I was diagnosed with Endometriosis in early 2020, doctors asked me to experiment with my diet. One of the first steps were going dairy free and caffeine free. My instant reaction - "I can't stop drinking the coffee! I stop drinking coffee, I stop doing the standing, and the walking, and the words-putting-into-sentences doing." Literally my case 2 years back! Everything was about coffee. My morning – start of office – post lunch – evening break – after work; My friends argued about me having caffeine in my veins more than blood. The aroma of coffee itself was intoxicating for me. Being thrown into the uncharted territory of learning to live
Learn MoreMasturbation, self pleasure...it is a great way to learn yourself and your body, and honestly, it is pure magic! Typically, our sex drives goes into overtime when it is time for our periods but it is a mess to have, but masturbation can have some positive effects for alleviating your period pain especially if you experience PMS symptoms. PMS is caused due to how the body responds to a normal menstrual cycle, which is brought on by the changing levels of estrogen, progesterone, serotonin, the hormone that stabilizes the mood. The decrease of serotonin levels during the onset of the period, can create PMS symptoms, as when estrogen levels drops, so does serotonin.
Learn MoreWhen it’s the onset of your period, do you suddenly get extremely fatigued? Sometimes falling asleep uncontrollably? You could possibly be dealing with Menstrual-related Hypersomnia, which reoccurs about a week prior to the start of your menses. Hypersomnia itself causes you to feel an excessive amount of sleepiness throughout the day, affecting concentration and energy levels. Although excessive sleep and/or sleepiness is a main symptom other symptoms can include: a decrease in motivation and activity, frequent mood changes, mental slowing like brain fog, and sometimes derealization, an altered perception causing your worldly reality to shift. At the second half of your
Learn MoreBlood clots during your period is something we all experience but have you ever wondered why they form? And why you may have so many? Although clots are normal and a natural defense mechanism for the body, blood clots are a mixture of blood cells, uterine lining tissue, and proteins in the blood which are used to aid in regulating its flow. As your body is preventing losing too much blood, it will form blood clots through a combo of plasma (liquid portion of blood) and platelets (blood cells that bind to form clots). As your lining sheds during the period, small blood vessels will bleed. Clots can also be mistaken for clumps of endometrial tissue. During the period, endometrial
Learn MoreYou could fly to the moon 456 times before getting an Endometriosis Diagnosis, study finds. - Alice Broster of Forbes recently published an article that gives a peek into the life of women suffering from Endometriosis. In the time it takes for women to obtain an accurate diagnosis, she could - fly to the moon 456 times, run 14,231 marathons, climb mount Everest 45 times! - Ughhh. This one got me. I have said this before - #1in10 women! Currently, 200 million+ women are affected by this disease around the world. For us, this journey to the right diagnosis averages between 7 to 12 years. In some cases, it takes more than 14 years to just diagnose.
Learn MoreThe thyroid gland is an important gland that plays a major role in your reproductive system and health. Shaped like a butterfly and located at the front (and base) of your neck, the thyroid is a small-hormone producing organ that directly affects the ovaries and indirectly interacts with sex hormone-binding globulin (SHBG), a protein that binds sex hormones. The thyroid also regulates a plethora of the body’s functions such as your metabolism, body temperature, and heart rate. Depending on how much excess or how little hormone your thyroid makes, may make you feel restless or tired, or lose or gain weight. When your thyroid is dysfunctional (not producing enough
Learn MoreLeukorrhea, normal vaginal discharge is comprised of fluid and bacteria from the cells located in the vagina. It aids in lubrication and the removal of bacteria from the vagina. Most women produce a little under a teaspoon, (4 milliliters) of white or clear discharge every day. Prior to your period, discharge tends to be cloudy or white. This is due to the increase of the hormone, progesterone, and is involved in both the menstrual cycle and pregnancy. In other phases of the menstrual cycle, when the body has increased levels of estrogen, the vaginal discharge tends to be more clear and watery. Throughout the menstrual cycle, there is a fluid or gel-like discharge
Learn MoreAnxiety is something we’ve all dealt with. On a daily basis, anxiety may affect us in many ways, but what about how much anxiety we draw when it surrounds our period? When the start of your period is coming, our anxiety about the period itself along with its symptoms comes in full throttle, but why? Anxiety, which is a symptom of PMS, onsets in response to the changing levels of the reproductive hormones, estrogen and progesterone. These hormones will rise and fall dramatically during the luteal phase of menstruation, which is the stage that occurs after ovulation and before your period begins. Simply, as your body prepares for pregnancy it will increase hormone
Learn MoreDyspareunia and Endometriosis often go hand in hand as it is one of the major symptoms when being diagnosed. By definition, dyspareunia is difficult or painful sexual intercourse and as one of the tale tell signs of Endometriosis, it’s crucial to tell your doctor if you’re experiencing pain during sex. When misplaced Endo tissue is growing, it causes inflammation and scarring. Behind the uterus is the cul-de-sac, or Pouch of Douglas, which is normally lined by the smooth peritoneum, the skin-like sheet of tissue that covers the uterus and vagina anteriorly (in front), and the rectum posteriorly (in back). This keeps the rectum, vagina, and uterus free and clear of each
Learn MorePostoperative depression, it’s a medical phrase that is not often discussed, but one that exists. With everything that comes with having a surgical procedure, depression is the last to be mentioned and physicians should be more aware of how traumatic an invasive surgery is and the effect it can have on a person especially when it’s their first time. During surgery, post-op depression can be a result of cognitive dysfunction, pain, lack of mobility, anxiety over possible complications, dependency upon others, and a compromised immune system. Additionally, general anesthesia (a mixture of gasses and drugs to sedate prior to surgery) may also be responsible for the
Learn MoreLet’s face it, discharge is annoying. While discharge is completely normal, a lot of times when we discharge we assume the worst. There are many factors that can play into producing discharge and the colors associated. The job of healthy discharge is to keep the vagina clean, keep infections away, and to provide lubrication. As your body’s needs changes, so will the discharge. Discharge will also increase during sex in the prevention of discomfort and irritation. It will also thicken during ovulation to help sperm on their journey to the egg for potential pregnancy. Your vaginal discharge is a reflection of your health and when it begins to smell, becomes consistent, is
Learn MoreWater makes up 70% of the human body and most often than not, we don’t consume as much water as we should. In order to maintain your body temperature, waste removal, lubricating joints, your body needs water. Dehydration can cause extreme thirst, dizziness and fatigue, and more but when it involves your period, we are more likely to be dehydrated during that time, causing muscular pain due to the lack of oxygen reaching your red blood cells. At the start of the menstrual cycle when your progesterone and estrogen levels recede, your body can retain water. When your body retains water the fluids will leak into the surrounding tissues instead of staying in your blood
Learn MorePeriod pain is a common issue we all share. Every month it seems to be the same dance when it comes to our period, most times than not causing us to hate our period. Here are 10 things you should do to decrease your period pain. Choose Herbal Teas over Coffee We love caffeine but honestly, it’s not good for us. Herbal teas contain anti-inflammatory properties and antispasmodic compounds which may decrease muscle spasms within the uterus (cramping). They can also provide relief from stress. Red Raspberry, Chamomile, Ginger, Fennel, Peppermint & Cramp Bark teas are some that may help. Get A Massage It sounds simple but it’s honestly one of the best
Learn MoreStress plays an important role in our lives and even more, with our periods. It is important to keep your stress levels low as we all know stress can be a literal killer, but how does stress have an effect our periods? When stressed, the body will activate a hormonal pathway called the hypothalamic-pituitary-adrenal axis (HPA). When the HPA axis is activated the levels of cortisol and the corticotropin-releasing hormone (CRH) will increase. These three entities (HPA axis, cortisol, and CRH) all work together to aid in controlling the stress response of the body. The release of CRH and cortisol can cause normal levels of reproductive
Learn MoreI am no Blogger. I am just here to share and hope to help more girls like me. A 30-year-old middle class girl from India. An Architect by profession. A basic girl who just wants to live her dreams. I am no writer. But ever since Endometriosis entered my ordinary life and made it extra-ordinary, I have a lot say. If I choose to share, I know that my vulnerability may help others finally receive their own diagnosis by learning about familiar symptoms. For those who have already been diagnosed, seeing me open up about my journey may help them feel less alone. I was lost. I was clueless. And I thought I was alone. The disease that affects 1 in 10 women, had me on my knees, left to feel
Learn MoreButt cramps. They come and go so fast you never have time to prepare for them. Sharp, shooting pain in the rectum that generally shows up when it’s time for your period. When your period is beginning, the endometrial cells (which lines the uterus) breaks down and gives off, prostaglandins. Prostaglandins is a hormone that can cause inflammation and contraction, including bowel and rectum muscle contractions. When pressure is put on the gluteal muscles from cramps, uterine swelling, and bloating tension will build, you may feel as if you have to urinate or have muscles spasms, which creates pain in the lower back, pelvis, and butt. According to some
Learn MoreSugar, the lover and culprit in many of our lives. We love it but often times it does not really love us back. Have you ever wondered why we crave sugar during that time of the month? Did you know that sugar adds to painful periods and can aggravate your PMS symptoms? By nature, sugar is inflammatory. It increases the blood supply in the uterus, which will lead to extreme water retention that causes abdomen pain. Estrogen and progesterone controls the menstrual cycles and blood glucose. When the body experiences fluctuations in blood sugar levels it is typically attributed to a certain point within the monthly cycle. We crave sugar because our body’s
Learn MoreSugar. It’s everywhere and in everything. It often provides us with a burst of energy to help us throughout our day, but for women living with Endometriosis, sugar is not our friend. The endocrine system rules our hormones. Glucose essentially feeds the entire body and the systems that function within it, so when the blood sugar levels are not balanced, the body will view this as a stressor and turn on the stress hormones: adrenaline and cortisol. Sugar causes an effect on the insulin hormone and after consuming foods that contains a lot of sugar, including bread and pastas, the amount of insulin within the body will increase. When the insulin levels are high, most
Learn MoreHormones. They can either make life good or a living hell, but the key is finding the balance. Inside of the endocrine system there are 50 different hormones that secretes throughout the body, each being critical in preserving homeostasis. Many people suffer from hormonal imbalances and from there spawns a host of other issues into the body like Endometriosis, diabetes, PCOS, heavy bleeding, fatigue, dizziness and more. Although there are many hormones, here are the top five that play a vital role in your life: 1. Cortisol: produced in your adrenal gland, Cortisol aids in regulating blood sugar,
Learn MoreStress. It is a major problem for many people, a lot of times killing them if not managed properly, but when an issue arises and surgery (minor or major) is the answer, their stress goes to a totally new place. Surgical Trauma, defined as, “any injury produced by or related to major surgery”, is more common than one may tend to think. Recognized by surgeon Francis Moore, trauma begins before a patient even enters the operating room, before being put under general anesthesia, and before the first incision. It begins when a patient becomes aware of what is in store for them. The minute the word “surgery” is mentioned as course of treatment, the anxiety bell
Learn More“Black people can handle higher tolerances of pain more than other races, particularly the white race.” This is a myth that has been surrounding Black people for centuries, leading everyone to believe that the pain threshold of this particular race is of almost superhuman strength. It is a myth that is not only false, but one that is also detrimental to Black people, especially Black women, and is built on many traumatic experiences. This notion of pain tolerance came from the days of slavery when Black people were operated on without any anesthesia, making slaves accustomed to pain – not raising their pain threshold. The idea that this particular trait was handed
Learn MoreHave you ever heard of the phrase, “the wandering womb” or “uterine suffocation”? It is the belief that the uterus could become displaced and cause many of the womb issues in women. Originating in ancient Greece, this ideology suggested that the uterus could and does “wander” throughout the body. For philosophers Plato and Hippocrates, the belief that women’s uteruses can travel, explained why men and women differ. Physician Aretaeus of Cappadocia, who believed that the womb was “an animal within an animal” also believed that it could move up, down, left or right to bump into the liver or spleen. He
Learn MoreHealth equity, racial bias are two subjects frequently discussed within the Endometriosis community. For a lot of Black women and women of color who are struggling, it could take longer than average to receive a diagnosis for Endometriosis. Outside of the disease being complicated to diagnose itself, race and environment plays a huge role. While Asian women are likely to be diagnosed sooner, Black women are less likely to be diagnosed with Endometriosis than Caucasian women. The stigma that Endometriosis only finds its way to those who are successful and high achieving, is extremely deadly, and although the mystery’s and myths of Endo are continuously being shattered, they
Learn MoreThe “H” Word. It is a word we hate hearing yet seem to hear so often when living with Endometriosis, and it is the hysterectomy. Whether it be partial (removal of the uterus) or total (removal of the uterus and cervix, and often times the fallopian tubes and ovaries), it is typically among one of the top three treatment options offered when diagnosed with Endometriosis for Black women and women of color. A hysterectomy requires surgery and is a final decision, and while there are plenty of treatment options available, why is it often offered as treatment first? In my experience, after receiving my diagnosis, a hysterectomy was offered as a means of treatment by a
Learn MoreLiving with Endometriosis while working a full-time or part-time job especially when you have to physically be there is difficult to say the least. As we know all too well, Endometriosis plagues our daily activities causing us to be confined to the bed more times than not. When we think of Endo and the long-term effects that it has on our lives, we typically forget to think about our lives in the workplace. Since the beginning of my time as a worker bee, my period has always caused me to miss days in the workplace. Most times, I try to work through the pain, but that does not always happen. With women who have severe Endometriosis, the time spent away from work can be more than
Learn MoreThroughout our experiences of living with Endometriosis, we are not exempt from the experiences we live through in other areas of our lives. There is life happening everyday as we suffer with the symptoms that Endometriosis brings. Here is a story of how Endometriosis and life happened at the same time and how we fight through it bravely and with resilience. "The first time I knew my Endo was real... Almost three years ago, I woke up in pain and stayed in bed all day. I could barely move. Months earlier I had been diagnosed with IBS, but I knew this was something else. I was experiencing another flare and none of the 8 medications I was taking relieved my pain. The sun
Learn MoreHaving Endometriosis can be tiring and can really have an effect on our eating habits. Sometimes, especially in the beginning of our Endo journeys, we don’t know that foods are a direct link to what’s going on with us. A lot of the foods we consume causes inflammation, which is a top trigger for Endo, and although it can be hard to do changing your diet and giving up foods, we love can help to begin the healing process. For me, dairy was the hardest to give up. I loved cheese and it had to be on just about everything I ate, but when I learned that the dairy (cheese especially) could cause estrogen dominance, I knew I had to let it go. I began my journey to juicing. My body
Learn MoreYour menstrual cycle is a cycle that most people believe is your monthly period, but in actuality your monthly period is apart of your menstrual cycle. The menstrual cycle is a monthly hormonal cycle that prepares the female body for pregnancy and consists of four phases: menstruation, the follicular phase, ovulation and the luteal phase. The length of a menstrual cycle varies upon each person and can fluctuate throughout your life, but they usually last between 24-35 days. The way you count your menstrual cycle is from the first day of your period to the day before your next period is set to begin. For instance, if my period began March 4 and is set to begin again
Learn MoreSanitary pads and tampons are staples for period maintenance but for years they have probably been one of the causes of our debilitating period problems. Unbeknownst to us, most sanitary products on the shelves like Kotex, Always, Stayfree, Carefree, and others we are accustomed to have chemicals in them that are harmful to our bodies. Until recently, if you looked for the ingredient labels on sanitary products you would not find them, as most brands label their products as 100% cotton, but what else do these important items contain? For starters, most products are not made with cotton but actually synthetics like Super Absorbent Polymers (SAPs) or Rayon and are bleached with
Learn MoreDefined by Merriam-Webster, barren is “not reproducing, such as being incapable of producing offspring – used especially of females or matings; not yet or not recently pregnant.” This term and more importantly, the emotion behind it are what many women experience today especially when living with Endometriosis, the leading cause of infertility predominately in Black women, yet it’s not being discussed much. When I was diagnosed with Endometriosis, I was told my fertility had been cut in half and I needed to decide on what my next steps would be. Most physicians I saw would suggest having a baby in that moment considering my age in
Learn MoreWithin your menstrual cycle there are some irregularities that can occur causing a menstrual disorder with a host of symptoms. As someone who was diagnosed with Pre-Menstrual Syndrome and Dysmenorrhea, dealing with a disorder on top of Endometriosis can be extremely tough. Below we list the four menstrual disorders and their differences. Premenstrual Syndrome (PMS): Those uncomfortable symptoms that disturbs your entire day or normal function during your cycle are considered PMS. The symptoms can vary from hours to days and the symptoms you may experience such as, headaches, fluid retention, irritability, fainting, decreased coordination and more, are based upon each
Learn MoreManaging your period is a full-time job when it causes issues like heavy bleeding, nausea, dizzy spells, and having to refrain from life’s many activities. If your period pain is anything like mine, over the counter or stronger medications do not work, so herbs may be a better option for you. Herbs are powerful and contain many medicinal properties to help with a plethora of ailments. From teas to tonics to steaming, herbs can be used in many ways to heal the body. Below are four super herbs you need to manage your period pain. Dong Quai Root: Sometimes known as Chinese Angelica, Dong Quai aids in treating dysmenorrhea, hot flashes due to menopause, the lack or
Learn MoreWhen you’ve been diagnosed with Endometriosis, your entire life changes, but the biggest lifestyle changes to be made is diet. The foods we eat contribute tremendously to our well-being and with Endometriosis it seems like just about anything can cause a flare up. Outside of flare ups, the pain we experience during our period can be affected upon what we eat. Below are five things we should absolutely stay away from as Endometriosis patients. Caffeine: Let’s face it, we all love a good coffee, but if you’re living with Endometriosis then it’s not in your best interest to consume it. Outside of caffeine causing inflammation, caffeine may also increase
Learn MoreIf you’re struggling with Endometriosis, fibroids, or any other reproductive disease it seems as if having a heavy blood flow during your period will never change. No matter what you try like different contraceptives, Lupron, or progesterone creams to balance the hormones, nothing helps. The bleeding seems to grow heavier and heavier as the months go by and the pain intensifies as well. In my journey of healing, I’ve discovered ways to help lighten your period flow. Below are five tips: Key Limes: Not limes, KEY LIMES. Key limes help to reduce inflammation, is a good source of magnesium, and help with digestion. If you juice 2 key limes into a shot glass or cup
Learn MoreOut of everything that comes with receiving an Endometriosis diagnosis (or any diagnosis for that matter), the hardest issue to tackle is how to advocate for yourself. Getting a doctor to believe your pain enough to look deeply and genuinely into it, is why women, especially African-American women and women of color struggle to receive a diagnosis. Even advocating to your family can be an issue when no one truly believes your pain. Below are nine ways to be your biggest advocate: Create a list of symptoms: Writing out a list of symptoms you experience will aid in your doctor’s visit. As patients, we’re nervous when speaking with our doctors, but if we create a
Learn MoreLaparoscopic procedure is a minimally invasive procedure commonly used to diagnose Endometriosis as well as to remove mild to severe endometriosis tissue. With this particular procedure, a small abdominal incision is created to insert a laparoscope, a lighted viewing instrument. “Lap surgery” as it is typically referred to, is a difficult procedure to endure and it’s important to be well prepared prior to. Here are ten tips to prepare for a lap procedure: Recovery time is typically 6-8 weeks, not 4: In most cases, surgeons will tell you recovery time after surgery is 4 weeks – it is not. Your body needs more time to recover. Although the procedure is
Learn MoreLiving with Endometriosis after receiving a diagnosis can be difficult. Readjusting has its downfalls but understanding Endometriosis and its stages can aid you in your journey to a manageable and healthy quality of life. Here are the four stages: Stage I (Peritoneal Endometriosis): Located on the peritoneum, the membrane that lines the abdomen, stage I is considered to be minimal endometriosis implants that are small and shallow. Stage II (Ovarian Endometriosis): mild endometriomas (cysts) found in the ovaries that run the risk of rupturing and spreading the endometriosis tissue to other nearby organs. The implants are deeper than the surface and superficial implants found in
Learn MoreEndometriosis is becoming more talked about, yet still extremely hard to detect. With many symptoms associated, it’s hard to decipher if asking your doctor about Endometriosis is right for you. Often times, you’ll find women who suffer from Endometriosis have painful periods, but sometimes that's not always the case. Some women who have widespread Endometriosis may have little or no pain during their period, while other women (like myself at the time of diagnosis) have mild Endometriosis but extreme period pain. Other common symptoms and signifiers, aside from painful periods to possibly detect Endometriosis include: Severe abdominal cramping Heavy
Learn MoreThe myths that surround Endometriosis are astounding. Whether it be as small as hair type or as grand as racial bias, what people believe about Endometriosis can be misconstrued as fact and can cause a prolonged diagnosis in women. Let’s dispel some myths about living with Endometriosis. 1. MYTH: Endometriosis is a “Rich White Woman’s disease”. FACT: Endometriosis affects an estimate of 1 in 10 women worldwide and is growing steadily. Some believe women with Endometriosis are extremely ambitious career women who tend to have a particular economic status and who typically do not want children until their late 30s. This myth can cause
Learn MoreHave you ever been in the middle of a sentence and lost your train of thought? Forgotten a name? Even struggled to complete a simple task? It happens. We all have “brain fart” moments, but when it happens more often than not, you start to wonder if something else is going on. Something deeper. Before I was diagnosed with Endometriosis, I could remember everything – literally to the smallest detail and at an instant, but when Endo began to plague my life, it did the same for my memory. It started to fade and became noticeable when my brother would ask me to do something. I would think, searching my brain for answers, and nothing would come. A literal blank
Learn MoreLupron Depot. The chemotherapy treatment they don’t warn you about. When I was introduced to Lupron Depot in 2014 after being diagnosed with Endometriosis, I did not know the ride I was in for. I had previously tried two forms of birth control pills, with no avail, so my doctor suggested we try Lupron Depot as a form of treatment. Looking for any relief, I accepted, and was told I’d need to receive an injection every three months for a six-month period. What I wasn’t told was that Lupron is a chemotherapy treatment. A treatment that is also used for men with prostate cancer. After adjusting to the Lupron, I was swiftly hit with the menopausal side effects.
Learn MoreTo have a painful period is a job within itself, but to have a painful period while dealing with Endometriosis (unknown at that) becomes a much more difficult job. My 20s was a difficult time for me. Juggling college, collegiate activities, friends, and work all while struggling to manage my debilitating period was a chore. As the months went by, my period was seemingly getting worse. In many instances, I needed emergent care, but I was always told my period was normal, so I never sought help further than an OB/GYN. It wasn’t until a traumatizing moment during my period when I began to understand that this was not the case. It’s day three of my cycle – the worst day out
Learn MoreSo often we get questions in our Facebook group about diagnostic studies for endometriosis. Patients are told repeatedly, your MRI/CT Scan/US/colonoscopy showed nothing, so you are disease free. Often they are told by family, friends, and doctors alike to stop obsessing about their symptoms, because they do not have endometriosis. This makes the path to diagnosis long and difficult for the patient. Since classic endometriosis symptoms are so pervasive and painful, these women persist in seeking answers. Still, on average, it takes 9 years to get a diagnosis. While scans can RULE IN endometriosis (particularly deep infiltrating endometriosis and endometriomas), they CANNOT
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Appeared in the The Atlantic, written by Ashely Fetters (10/08/2018) It started early in the year. In January, a widely cited Vogue cover story on the tennis great Serena Williams, who gave birth to a daughter in September of 2017, told the harrowing tale of how Williams had to urgently insist to the hospital staff in her recovery room that what she was experiencing after her C-section was a pulmonary embolism in order to get the treatment she needed to stay alive. “The nurse thought her pain medicine might be making her confused,” the story reads. A month later, Vogue published an essay by the Girls creator Lena Dunham on her
Learn MoreTEMPLE THERAPEUTICS B.V. MOMENTUM BUILDS INTO $45M RAISE TO ADVANCE PIPELINE; WINS $3 MILLION FUNDING IN EUREKA EUROSTARS PROGRAMME TO DEVELOP NOVEL THERAPY FOR OVARIAN AND SOLID CANCERS (AUGUST 20th, 2019 – GELEEN, THE NETHERLANDS)-- Temple Therapeutics, B.V. (the “Company” or “Temple”), a clinical stage biotechnology company engaged in the development of first-in-class therapeutics for post-surgical adhesion prevention, endometriosis, and oncology, announced today that the Company and its consortium partners will be receiving non-dilutive funding of $3 million to develop a novel therapeutic based on the discovery of a novel target found in a
Learn MoreGeleen, The Netherlands Temple Therapeutics BV (the “Company” or “Temple”)- September 10, 2018-Temple, a clinical stage biopharmaceutical company focused in developing therapeutics for fibrosis and oncology, announces the publication of groundbreaking mechanistic data for Evitar™ in Reproductive Sciences, a peer reviewed journal of the Society of Reproductive Investigations. Post-surgical adhesions are broadly recognized as the single greatest cause of surgical complications. Moreover, they have evaded effective intervention, until
Learn MoreTemple Therapeutics B.V.'s vision is to “Challenge, Collaborate, Create” to bring innovative, impactful therapies which simplify and increase quality of life. Achievement of which must be rooted in evidence, driven by science and the method of questioning. For 129 years, since Dembrowski’s first publication about post surgical adhesions, complete prevention is still elusive. Advancement in science and those willing to challenge the paradigms led to the hypothesis that adhesion formation is the end result of an amplified fibrotic process. Led by Temple's Chief Scientific Officer, Lynne Robertson, PhD. and in collaboration with leading
Learn MoreWomen Focus On Short-Term Concerns Prior to Pelvic Surgery, Not Lasting Complications Red Bank, NJ – Although more than half of the country's women will have some type of pelvic surgery and are therefore at risk for surgical adhesions, a survey released this month by the not-for-profit National Women's Health Resource Center (NWHRC) finds that women are largely unaware of the health risks associated with
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